Article ID Journal Published Year Pages File Type
10956299 Molecular and Cellular Endocrinology 2012 11 Pages PDF
Abstract
► This review focuses on the highly dynamic mode of GR action at the chromatin template. ► Stochastic GR action is discussed in light of the glucocorticoid ultradian rhythm. ► GR slow cycling on chromatin is directed by the pulsatile ligand. ► GR slow cycling directs a novel gene pulsing effect. ► Cyclical activity of cofactors and histone acetylation at a GR regulated gene.
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Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
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