Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10956299 | Molecular and Cellular Endocrinology | 2012 | 11 Pages |
Abstract
⺠This review focuses on the highly dynamic mode of GR action at the chromatin template. ⺠Stochastic GR action is discussed in light of the glucocorticoid ultradian rhythm. ⺠GR slow cycling on chromatin is directed by the pulsatile ligand. ⺠GR slow cycling directs a novel gene pulsing effect. ⺠Cyclical activity of cofactors and histone acetylation at a GR regulated gene.
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Authors
Becky L. Conway-Campbell, John R. Pooley, Gordon L. Hager, Stafford L. Lightman,