Article ID Journal Published Year Pages File Type
10956303 Molecular and Cellular Endocrinology 2012 12 Pages PDF
Abstract
► This paper reviews the structural dynamics of steroid hormone receptors. ► The hinge region and amino-terminal domain (NTD) are intrinsically disordered regions of receptors. ► The hinge and NTD form multiple conformations upon binding co-regulatory proteins or DNA. ► Due to structural flexibility, the hinge and NTD are sites of post-translation modifications.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
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