Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10956303 | Molecular and Cellular Endocrinology | 2012 | 12 Pages |
Abstract
⺠This paper reviews the structural dynamics of steroid hormone receptors. ⺠The hinge region and amino-terminal domain (NTD) are intrinsically disordered regions of receptors. ⺠The hinge and NTD form multiple conformations upon binding co-regulatory proteins or DNA. ⺠Due to structural flexibility, the hinge and NTD are sites of post-translation modifications.
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Authors
Krista K. Hill, Sarah C. Roemer, Mair E.A. Churchill, Dean P. Edwards,