| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10956540 | Molecular and Cellular Neuroscience | 2012 | 7 Pages |
Abstract
We found that reduced MARK2 expression resulted in altered migratory patterns and stalled neuroblasts in the rostral migratory stream (RMS). In agreement with the observed migratory defects, we report a diminution of the proportion of cells reaching the OB layers. Our study reveals the involvement of MARK2 in the maintenance of the migratory direction in postnatally-generated neuroblasts and consequently on the control of the number of newly-generated neurons reaching and integrating the appropriate target circuits.
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Authors
Sheyla Mejia-Gervacio, Kerren Murray, Tamar Sapir, Richard Belvindrah, Orly Reiner, Pierre-Marie Lledo,