| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10958045 | Neurochemistry International | 2013 | 7 Pages |
Abstract
⺠Glutamate (10 mM) reduced hippocampal slice viability. ⺠Glutamate inhibits PI3K/AKT pathway and activated p38MAPK and ERK1. ⺠ConBr, a lectin from Canavalia brasiliensis, prevented glutamate-induced toxicity. ⺠The neuroprotective mechanism of ConBr was dependent on PI3K/Akt pathway.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cell Biology
Authors
Amanda V. Jacques, Débora K. Rieger, Mariana Maestri, Mark W. Lopes, Tanara V. Peres, Filipe M. Gonçalves, Daniela Z. Pedro, Carla I. Tasca, Manuela G. López, Javier Egea, Kyria S. Nascimento, Benildo S. Cavada, Rodrigo B. Leal,