| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10958056 | Neurochemistry International | 2012 | 9 Pages |
Abstract
⺠Chronic alcohol exposure can adversely affect neuronal morphology, synaptic architecture and associated neuroplasticity. ⺠A total of 28 proteins were significantly altered in the striatum of 8 month beer drinking rats relative to controls. ⺠Five of the total identified proteins were involved in dopamine-related pathways.
Keywords
adenyl cyclaseDHAPTCAPPPcGMPV-ATPaseNOSGBPeNOSDARPP-32TPPMSTPP1G3PDHalcohol preferringNADH dehydrogenaseHigh Alcohol DrinkingCREBVacuolar ATPaseROSHydrogen peroxideAldose reductaseStriatumAlcoholProtein expressionTyrosine phosphatasetyrosine hydroxylaseHADDopamineSODendothelial nitric oxide synthaseSuperoxide dismutaseMethylglyoxalpentose phosphate pathwayRatNitric oxidenitric oxide synthaseH2O2protein phosphatase-1tricarboxylic acid cycleglycerol-3-phosphate dehydrogenaseReactive oxygen species
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Authors
Mohammed Abul Kashem, Selina Ahmed, Ranjana Sarker, Eakhlas U. Ahmed, Garth A. Hargreaves, Iain S. McGregor,