| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10958068 | Neurochemistry International | 2012 | 12 Pages |
Abstract
⺠Food restriction augments somatostatin receptor density in a CREB-mediated mechanism. ⺠Increased hippocampal somatostatinergic tone has orexigenic effects. ⺠Downregulation of somatostatinergic system potentiates leptin effects. ⺠Leptin modifies the concentrations of molecules involved in cAMP regulation. ⺠Leptin antagonist normalizes abnormal somatostatin signaling induced by leptin.
Keywords
STAT3signal transducer and activator of transcription factor 3SRIFSOCS3IFNγGRKsomatostatin receptor subtypeTTBSSSTSDSCREBG-protein-coupled receptor kinaseadenylyl cyclaseinterferon-γinterleukinsodium dodecyl sulfatesuppressor of cytokine signaling 3SomatostatinLeptinfood restrictionHippocampuscyclic AMP response element binding proteinSomatostatin receptor
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cell Biology
Authors
Arancha Perianes-Cachero, Emma Burgos-Ramos, Lilian Puebla-Jiménez, Sandra Canelles, MarÃa Paz Viveros, Virginia Mela, Julie A. Chowen, Jesús Argente, Eduardo Arilla-Ferreiro, Vicente Barrios,