| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10958071 | Neurochemistry International | 2012 | 7 Pages |
Abstract
⺠Acute and subchronic treatments with pindolol induces increases in brain 5-HT synthesis. ⺠The effects are more pronounced after subchronic treatment. ⺠The effects are most likely due to the antagonism on 5-HT1A or 5-HT1B autoreceptors. ⺠Observed effects suggest the desensitization of autoreceptors.
Keywords
SNRVTAFCxRPAVHIHYPα-[14C]methyl-l-tryptophanCA3PCXMBFDTHRPO5-hydroxytryptamineCPLACXSNC5-HTSPDCPMcornu ammonis 3AmygdalaAutoradiographySprague–DawleyscxAMYPineal bodydHImedial forebrain bundleventral thalamusdorsal thalamusMedial geniculateraphe magnusDorsal raphé Median rapheLateral geniculateSuperior oliveinferior oliveSuperior colliculusfrontal cortexSensory cortexAuditory CortexVisual cortexParietal cortexclaustrumdorsal subiculumSprague–Dawley ratsSerotonin synthesis rateventral tegmental areaaccumbens nucleusanterior olfactory nucleusraphe pallidus nucleusraphe obscurus nucleusHypothalamusventral hippocampusdorsal hippocampusCaudate putamenVthPindololcingulate cortexInferior colliculusGlobus pallidus
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Authors
Ivan Skelin, Maraki Fikre-Merid, Mirko Diksic,