| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10958092 | Neurochemistry International | 2013 | 8 Pages |
Abstract
⺠Recombinant AIF does not function as an antioxidant enzyme. ⺠AIF deficiency causes a reduction in mitochondrial complex I. ⺠Changes in ROS are more likely due to electron transport changes than loss of AIF. ⺠AIF deficient mice do not get Parkinson's disease despite reduced complex I. ⺠AIF has pro-survival and pro-death roles that both modulate neuronal injury.
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Authors
Brian M. Polster,