Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10958094 | Neurochemistry International | 2013 | 7 Pages |
Abstract
⺠Substantial amounts of reactive oxygen species are generated in ischemic stroke. ⺠Oxidative stress occurs mainly at the time of reperfusion. ⺠Endogenous antioxidants cannot neutralise the toxic load of oxygen radicals. ⺠All components of the neurovascular unit are sources and targets of oxidative stress. ⺠Therapeutic strategies involve prevention or neutralisation of oxidative stress.
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Authors
Silvia Manzanero, Tomislav Santro, Thiruma V. Arumugam,