Article ID Journal Published Year Pages File Type
10958094 Neurochemistry International 2013 7 Pages PDF
Abstract
► Substantial amounts of reactive oxygen species are generated in ischemic stroke. ► Oxidative stress occurs mainly at the time of reperfusion. ► Endogenous antioxidants cannot neutralise the toxic load of oxygen radicals. ► All components of the neurovascular unit are sources and targets of oxidative stress. ► Therapeutic strategies involve prevention or neutralisation of oxidative stress.
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