Article ID Journal Published Year Pages File Type
10958111 Neurochemistry International 2013 12 Pages PDF
Abstract
► Low amounts of retinoic acid (RA) protect against irreversible proteasome inhibition induced cell death. ► Pretreatment with RA reverses oxidative stress and related cell death despite no changes in protein ubiquitination. ► Activation of the PI3/AKT pathway is essential for RA associated neuroprotection.
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Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
Preview
Retinoic acid protects against proteasome inhibition associated cell death in SH-SY5Y cells via the AKT pathway
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