| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10958126 | Neurochemistry International | 2012 | 13 Pages |
Abstract
⺠Microarray study of primary mouse cortical neurons treated with oligomeric Aβ1-42 (ADDLs). ⺠Down-regulation of genes involved in the biosynthesis of cholesterol and other steroids/lipids. ⺠Abca1, involved in cholesterol transport and linked to Alzheimer's, up-regulated. ⺠Interactions between Aβ and cholesterol potentially important in Alzheimer's pathology.
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Authors
Bilal Malik, Cathy Fernandes, Richard Killick, Richard Wroe, Alessia Usardi, Ritchie Williamson, Stuart Kellie, Brian H. Anderton, C. Hugh Reynolds,