Article ID Journal Published Year Pages File Type
10958127 Neurochemistry International 2012 7 Pages PDF
Abstract
► The divalent metal transporter 1 (DMT1) inhibitor, ebselen, reduces iron influx in SH-SY5Y cells. ► Ebselen inhibits the activities of cyclin-dependent kinase 5 and glycogen synthase kinase 3β. ► Ebselen attenuates iron-induced tau phosphorylation by inhibition of DMT1 up-regulation.
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Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
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Ebselen inhibits iron-induced tau phosphorylation by attenuating DMT1 up-regulation and cellular iron uptake
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