| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10958217 | Neurochemistry International | 2012 | 8 Pages |
Abstract
⺠Activation of presynaptic glutamate receptors triggers ROS generation in axon terminals. ⺠Effect of glutamate as well as NMDA and kainate is dose-dependent. ⺠NADPH oxidase is implicated in glutamate receptor agonist-induced ROS production. ⺠Kainate receptors can be considered as a major stimulator of ROS generation in axon terminals. ⺠Increased level of ROS potentiates GABA release.
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![Reactive oxygen species induced by presynaptic glutamate receptor activation is involved in [3H]GABA release from rat brain cortical nerve terminals](/preview/png/10958217.png "First Page Preview: Reactive oxygen species induced by presynaptic glutamate receptor activation is involved in [3H]GABA release from rat brain cortical nerve terminals")
Authors
A. Tarasenko, O. Krupko, N. Himmelreich,