| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10958225 | Neurochemistry International | 2012 | 12 Pages |
Abstract
⺠OCTN1/SLC22A4 is functionally expressed in the brain. ⺠OCTN1 is localized in both neuronal cell bodies and dendrites. ⺠Inhibition of OCTN1 increases intracellular oxidative stress. ⺠Inhibition of OCTN1 promotes cellular proliferation. ⺠Inhibition of OCTN1 suppresses neuronal differentiation and/or maturation.
Keywords
Gap43Sox2SLCUCP2intracerebroventricularHeme oxygenase-1HO-136B4i.c.v.Nrf2xCTOCTN1SYN1FBSmitochondrial uncoupling protein 2DMEMPBSacidic ribosomal phosphoprotein P0MAP2atRASmall interfering RNAROSsiRNAall-trans retinoic acidErgothioneineStriatumErGOProliferationDifferentiationsolute carrierTransporterDIVNeurite outgrowthdays in vitrofetal bovine serumSynapsin Icerebral cortexPhosphate-buffered salineDulbecco’s modified eagle’s mediumCerebellumSex determining region Y-box 2MidbrainBrain neuronHypothalamusHippocampusparaformaldehydegrowth-associated protein 43microtubule-associated protein 2high-performance liquid chromatographyHPLCReactive oxygen species
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Authors
Noritaka Nakamichi, Takayuki Taguchi, Hiroshi Hosotani, Tomohiko Wakayama, Takuya Shimizu, Tomoko Sugiura, Shoichi Iseki, Yukio Kato,