Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10958229 | Neurochemistry International | 2012 | 12 Pages |
Abstract
⺠Parkinsonian and dyskinetic monkeys show regional changes of brain 5-HT1A receptors. ⺠Striatal 5-HT turnover increased with l-DOPA regardless of the dyskinetic status. ⺠Cortical 5-HT1A receptors were lower in parkinsonian monkeys compared to controls. ⺠l-DOPA increased 5-HT1A receptors in the hippocampus and the cortex. ⺠Ro 61-8048 prevented the l-DOPA-induced 5-HT1A receptors increase in motor cortex.
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Authors
Golnasim Riahi, Marc Morissette, Daniel Lévesque, Claude Rouillard, Pershia Samadi, Martin Parent, Thérèse Di Paolo,