| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10958231 | Neurochemistry International | 2012 | 9 Pages |
Abstract
⺠Glioblastoma cells exhibit L1CAM expression which is regulated by TGF-β1. ⺠L1CAM and TGF-β1 are expressed in differentiated glioma stem-like cells. ⺠TGF-β1-mediated L1CAM assisted chemoresistance in gliomas/stem-like cells. ⺠Resistance is mediated by regulation of caspase-8 in gliomas/stem-like cells.
Keywords
GFAPFCSGBMMAP2GAPDHSox2bFGFMBPmyelin-basic proteinqPCRDMEMPBSEGFBSADMSODulbecco’s modified Eagle mediumbovine serum albuminDimethylsulfoxidefetal calf serumepidermal growth factorbasic fibroblast growth factorPhosphate-buffered salinequantitative real-time PCRGlial fibrillary acidic proteinmicrotubule-associated protein 2glyceraldehyde-3-phosphate dehydrogenaseGlioblastoma multiforme
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Authors
Janka Held-Feindt, Sabine Schmelz, Kirsten Hattermann, Rolf Mentlein, H. Maximilian Mehdorn, Susanne Sebens,