Article ID Journal Published Year Pages File Type
10958241 Neurochemistry International 2012 5 Pages PDF
Abstract
► CRFR1 agonists induce the release of GABA from the hypothalamus. ► CRF1 antagonists block the CRF/UCN1-induced release of GABA from the hypothalamus. ► UCN2 and UCN3 do not influence the GABA release from hypothalamic or limbic nuclei. ► Hypothalamic GABA may inhibit directly the HPA axis. ► Limbic GABA may stimulate indirectly the HPA axis.
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