Lycopene protects against trimethyltin-induced neurotoxicity in primary cultured rat hippocampal neurons by inhibiting the mitochondrial apoptotic pathway

Article ID	Journal	Published Year	Pages	File Type
10958254	Neurochemistry International	2011	9 Pages	PDF

Abstract

âº Lycopene protects against TMT toxicity in hippocampal neurons. âº Lycopene suppresses ROS production in TMT-treated hippocampal neurons. âº Lycopene blocks TMT-activated mitochondrial apoptotic pathway.

Keywords

CCK-8 BHT THF TMT CCCP DCFH-DA MPTP ΔΨm ROS mitochondrial permeability transition pore Tetrahydrofuran Trimethyltin TUNEL dichlorofluorescin diacetate cell counting kit-8 Lycopene Mitochondria Hippocampal neurons butylated hydroxytoluene Mitochondrial membrane potential Reactive oxygen species

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology

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Lycopene protects against trimethyltin-induced neurotoxicity in primary cultured rat hippocampal neurons by inhibiting the mitochondrial apoptotic pathway

Authors

Mingyue Qu, Zhou Zhou, Chunhai Chen, Min Li, Liping Pei, Fang Chu, Ju Yang, Yuan Wang, Li Li, Chuan Liu, Lei Zhang, Guangbin Zhang, Zhengping Yu, Denggao Wang,