| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10958279 | Neurochemistry International | 2011 | 8 Pages |
Abstract
⺠Aβ25-35 affected ganglioside expression in organotypic hippocampal cultures. ⺠Fibrillar Aβ25-35 increased GM3 labeling and reduced GD1b labeling. ⺠Non-fibrillar form of Aβ25-35 enhanced GM1 expression. ⺠Gangliosides could participate in the development of Alzheimer's disease. ⺠GM1 exhibited a neuroprotective effect against Aβ-induced toxicity in organotypic model.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cell Biology
Authors
Fernando Kreutz, Rudimar L. Frozza, Ana Carolina Breier, Valeska A. de Oliveira, Ana Paula Horn, LetÃcia F. Pettenuzzo, Carlos Alexandre Netto, Christianne Gazzana Salbego, Vera Maria Treis Trindade,