| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10958286 | Neurochemistry International | 2011 | 8 Pages |
Abstract
⺠Phthalate diesters inhibit [3H]CP-55940 and [3H]SR141716A binding to brain CB1-Rs. ⺠Phthalate monoesters are less effective inhibitors of [3H]radioligand binding. ⺠Inhibitory effects on G-protein activation and [3H]CP-55940 binding correlate well. ⺠Phthalates are low affinity, allosterically acting antagonists of CB1-R function.
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Authors
Kathleen M. Bisset, Amey S. Dhopeshwarkar, Chengyong Liao, Russell A. Nicholson,