Article ID Journal Published Year Pages File Type
10958291 Neurochemistry International 2011 4 Pages PDF
Abstract
► Calpain produces a truncation of GSK3β that removes the N-terminal inhibitory domain. ► GST-pull-down protocol is used to analyze the effect of that truncation on protein-protein interaction. ► N-terminal end is necessary for 14-3-3ζ, p53 and PKB interaction, but not for axin.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
Preview
Calpain regulates N-terminal interaction of GSK-3β with 14-3-3ζ, p53 and PKB but not with axin
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