Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10958297 | Neurochemistry International | 2011 | 12 Pages |
Abstract
⺠Stress is a risk factor for neuropsychiatric disorders. ⺠Stress/glucocorticoids enhance glutamate release in limbic/cortical areas. ⺠Enhanced glutamate release causes dendritic remodeling in select brain areas. ⺠Dendritic remodeling may induce volumetric reductions of brain areas in depression. ⺠Antidepressants prevent enhancement of glutamate release and dendritic remodeling.
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Authors
Laura Musazzi, Giorgio Racagni, Maurizio Popoli,