Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10958298 | Neurochemistry International | 2011 | 9 Pages |
Abstract
⺠LOC efferents release different transmitters in the cochlea, including dopamine (DA). ⺠DA release in the cochlea protects against noise exposure or ischemia. ⺠DA is released by a feed back loop involving the brainstem. ⺠DA release is also modulated locally in the cochlea (ultra-short feed back loop). ⺠Pharmacological enhancement of cochlear DA release could be used for otoprotection.
Keywords
5-HTNIHLAICAOGDDPOAEVGCCsTTXSNHLPresbycusisLSOOHCsNOSlateral olivocochlearHearing lossnoise-induced hearing lossdistortion product otoacoustic emissionorgan of CortiIHCtetrodotoxintyrosine hydroxylaseCochleaClinical treatmentDopaminelateral superior oliveSerotoninOuter hair cellsinner hair cellsAnterior inferior cerebellar arteryNeuroprotectionoxygen–glucose deprivationLoccochlear microphonicnitric oxide synthaseTinnitusCompound Action PotentialCaPsensorineural hearing loss
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Authors
Balázs Lendvai, György B. Halmos, Gábor Polony, Judit Kapocsi, Tamás Horváth, Máté Aller, E. Sylvester Vizi, Tibor Zelles,