| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10958313 | Neurochemistry International | 2011 | 7 Pages |
Abstract
⺠Corilagin attenuated tert-butyl hydroperoxide-induced oxidative injury in cultured N9 murine microglia cells. ⺠Corilagin inhibited tert-butyl hydroperoxide-induced apoptosis in cultured N9 murine microglia cells. ⺠Corilagin improved the activity of superoxide dismutase and total antioxidant capacity. ⺠Corilagin decreased intracellular reactive oxygen species and restored mitochondrial membrane potential. ⺠Corilagin upregulated Bcl-2 expression and downregulated the Bax/Bcl-2 ratio.
Keywords
GSHMMPNACDMEMFBStotal anti-oxidant capacityT-AOCDCFH-DAPVDFCorilagintBHPDcf2′,7′-dichlorodihydrofluorescein diacetate2′,7′-dichlorofluoresceinMTTN-acetylcysteineROSOxidative stressApoptosispolyvinylidene difluorideRh 123Rhodamine 123SODfetal bovine serumSuperoxide dismutaselactate dehydrogenaseLDHDulbecco’s modified eagle’s mediumtert-butyl hydroperoxideMitochondrial membrane potentialPropidium iodideGlutathioneReactive oxygen species
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Authors
Yiyan Chen, Chonghong Chen,