Article ID Journal Published Year Pages File Type
10958315 Neurochemistry International 2011 10 Pages PDF
Abstract
► Glucose and β-hydroxybutyrate metabolism were studied in cultured neurons using 13C. ► β-Hydroxybutyrate inhibits metabolism of glucose in GABAergic neurons. ► β-Hydroxybutyrate cannot substitute for glucose as energy substrate during activity. ► The presence of β-hydroxybutyrate affects aspartate but not GABA content. ► 13C in glutamate and GABA coming from β-hydroxybutyrate exceeds that from glucose.
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