| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10958331 | Neurochemistry International | 2011 | 9 Pages |
Abstract
ⶠThe suppression of P2X7 receptors during ischemia opened pannexin-1 hemichannels. The opening of hemichannels enhanced the release of ATP. The enhanced ATP release was reversed by co-treatment with pannexin-1 blockers. ATP, released via pannexin-1 hemichannels, activated P2X7 receptors. The activation of P2X7 in turn closed hemichannels during ischemia.
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Authors
Sadahiro Iwabuchi, Koichi Kawahara,