| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10958367 | Neurochemistry International | 2009 | 8 Pages |
Abstract
Our findings show that ER and mitochondria are in a close communication, establishing a dynamic ER-Ca2+-mitochondria interconnection that can play a prominent role in the neuronal cell death induction under particular stressful circumstances of PD pathology.
Keywords
TPGPMSFLBS6-HydroxydopamineTBSUPR1-methyl-4-phenylpyridiniumDTTMPTPdithiotreitolRh123CoQ1ubiquinonePBSMMPPDI6-OHDAFCCPMPP+ROSEndoplasmic reticulum stressLewy bodiesParkinson's diseaseTris–buffered salinesubstantia nigraRhodamine 123endoplasmic reticulumphenylmethylsulfonyl fluoridelocus coeruleusPhosphate-buffered salineCell deathMitochondriaUnfolded protein responseMitochondrial membrane potentialCHAPSCarbonyl cyanide 4-(trifluoromethoxy) phenylhydrazoneCalciumReactive oxygen species
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cell Biology
Authors
Daniela Moniz ArduÃno, A. Raquel Esteves, Sandra M. Cardoso, Catarina R. Oliveira,