Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10959090 | Seminars in Cell & Developmental Biology | 2012 | 8 Pages |
Abstract
⺠ChREBP/MondoA-Mlx transcription factors are activated by intracellular glucose flux. ⺠ChREBP/MondoA-Mlx regulate metabolic targets involved in glycolysis and lipogenesis. ⺠The intracellular glucose sensing system in conserved in multicellular animals. ⺠ChREBP/MondoA-Mlx and their regulators are potential therapeutic targets.
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Authors
Essi Havula, Ville Hietakangas,