Article ID Journal Published Year Pages File Type
10959096 Seminars in Cell & Developmental Biology 2012 8 Pages PDF
Abstract
► Blood vessels influence pancreas organogenesis and differentiation of its cell lineages. ► Aortic endothelial cells are required for early endocrine specification. ► Blood vessels suppress later pancreatic branching and exocrine differentiation. ► Understanding how blood vessels impact the developing pancreas and identifying candidate signals may improve replacement and regenerative therapies for diabetes.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
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