Article ID Journal Published Year Pages File Type
10959099 Seminars in Cell & Developmental Biology 2012 9 Pages PDF
Abstract
► Endocrine and exocrine ontogenies are highly intertwined. ► Multipotent pancreatic progenitor cells become developmentally restricted to central “trunk” and peripheral “tip” domains. ► Considerable heterogeneity exists among adjacent cells within the pancreatic ductal epithelial tree. ► Terminal duct and centroacinar cells display unique in vitro progenitor capacities.
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