Article ID Journal Published Year Pages File Type
10959113 Seminars in Cell & Developmental Biology 2012 6 Pages PDF
Abstract
► The A to I RNA editing modification has a regulatory role in innate immunity. ► The RNA editing enzyme ADAR1 increases viral proliferation. ► Distinguishing feature of ADAR1 is a Z-DNA/Z-RNA binding domain, Zalpha. ► Zalpha domains characterize proteins of the interferon response involved in the recognition of foreign nucleic acids.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
Authors
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