Early arterial differentiation and patterning in the avian embryo model

► Review of the avian vascular model with emphasis on the embryonic dorsal aorta(e) to study vessels cell recruitment, vessel positioning and remodeling. ► Review of recent studies showing how vascular inhibitors are key regulators of vessel positioning and regulate vascular remodeling where positive vascular factor expression (VEGF, FGF and Shh) remains unchanged. ► Models of how BMP-antagonists act as vascular inhibitors to influence vascular cell recruitment and vessel remodeling.