| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10959150 | Seminars in Cell & Developmental Biology | 2011 | 7 Pages |
Abstract
⺠Angiogenic sprouting of vessels occurs via specialization of endothelial 'tip' cells. ⺠Endothelial tip cells interpret environmental cues to direct vessel patterning. ⺠Each tissue bed has guidance cues to spatially regulate sprouting. ⺠Context-specific patterning cues yield stereotypical or 'free-form' vasculature. ⺠A tip cell fuses with its target, and the new vessel acquires a blood-bearing lumen.
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Authors
John C. Chappell, David M. Wiley, Victoria L. Bautch,