Article ID Journal Published Year Pages File Type
10959171 Seminars in Cell & Developmental Biology 2011 7 Pages PDF
Abstract
► Mediator complex gene mutants have diverse phenotypes affecting many developmental processes. ► Mutants in the same Mediator complex gene in different species have distinct phenotypes. ► Mutant phenotypes reveal that Med12 and Med13 have similar functions in multiple species. ► Mutant phenotypes reveal that Cdk8 and CycC do not overlap in function with Med12 and Med13. ► At present no overall correlation exists between complex location and mutant phenotype.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
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