Article ID Journal Published Year Pages File Type
10959189 Seminars in Cell & Developmental Biology 2012 7 Pages PDF
Abstract
► This review focuses on nuclear trafficking and functions of growth factor receptors, principally members of the ErbB family. ► It discusses the pathways and signals which contribute to nuclear translocation of these receptors. ► It outlines the functions of nuclear growth factor receptors. ► It describes the application made of these observations to determining cancer prognosis and treatment response. ► It defines the challenges of further exploring the nuclear trafficking and functions of growth factor receptors.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
Authors
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