Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10959189 | Seminars in Cell & Developmental Biology | 2012 | 7 Pages |
Abstract
⺠This review focuses on nuclear trafficking and functions of growth factor receptors, principally members of the ErbB family. ⺠It discusses the pathways and signals which contribute to nuclear translocation of these receptors. ⺠It outlines the functions of nuclear growth factor receptors. ⺠It describes the application made of these observations to determining cancer prognosis and treatment response. ⺠It defines the challenges of further exploring the nuclear trafficking and functions of growth factor receptors.
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Authors
Ian G. Mills,