| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10959191 | Seminars in Cell & Developmental Biology | 2012 | 10 Pages |
Abstract
⺠Targeted cAMP reporters have facilitated a greater understanding of the compartmentalised nature of cAMP signalling. ⺠Signalling via cAMP is not necessarily retarded following receptor internalisation. ⺠Epac signalling is compartmentalised by virtue of Epac scaffolding proteins.
Keywords
GPCRPTHrPPDE4PTH-related peptideVECGRKPTHREpacPIP2EC couplingYFPSerca2RyRERMIBMXpKaTSHDNAPKCFPPDERyR2Sarcoplasmic reticulum Ca2+-ATPasecAMPG protein-coupled receptor kinaseSmall interfering RNAsiRNAcyclic adenosine 3′,5′-monophosphateadenylyl cyclaseEzrin Radixin MoesinFRETisobutyl-methylxanthineExcitation–contraction couplingReceptor internalisationSarcoplasmic reticulumVascular endothelial cellsphosphatidylinositol-4,5-bisphosphatePhosphodiesteraseCANThyroid-stimulating hormoneExchange protein directly activated by cAMPProtein phosphataseyellow fluorescent proteincyan fluorescent proteinmAKAPCalcineurinRyanodine receptorCardiac ryanodine receptorparathyroid hormone receptorG protein-coupled receptor
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cell Biology
Authors
Helen V. Edwards, Frank Christian, George S. Baillie,