Article ID Journal Published Year Pages File Type
10959194 Seminars in Cell & Developmental Biology 2012 6 Pages PDF
Abstract
► RNA-seq and other NGS-based approaches enable the analysis of non-coding transcriptomes. ► lncRNAs can be transcribed from promoters of coding transcripts, enhancers, repetitive elements, antisense to protein-coding genes, or separate from coding genes. ► lncRNAs are transcriptionally and post-transcriptionally regulated. ► Specific and dynamic lncRNA expression patterns and subcellular localisations provide insights into their functions.
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Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
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