| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10959223 | Seminars in Cell & Developmental Biology | 2012 | 11 Pages |
Abstract
⺠Classical cancer genes directly regulate metabolic enzymes. ⺠Genes encoding eight genes of four metabolic enzymes are mutated in cancer. ⺠Three oncometabolites inhibit α-KG dependent dioxygenases. ⺠Oncometabolites may link cancer genetics, epigenetics, and microenvironment.
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Authors
Eric K. Oermann, Jing Wu, Kun-Liang Guan, Yue Xiong,