| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10959472 | Seminars in Cell & Developmental Biology | 2005 | 8 Pages |
Abstract
The concerted action of extracellular signals such as BMP, Wnt, FGF, RA and Notch activate a genetic program required to transform a naïve ectodermal cell into a neural crest cell. In this review we will analyze the extracellular signals and the network of transcription factors that are required for this transformation. We will propose the division of this complex network of factors in two main steps: an initial cell specification step followed by a maintenance or cell survival step.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cell Biology
Authors
Ben Steventon, Carlos Carmona-Fontaine, Roberto Mayor,