| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10963456 | Vaccine | 2015 | 5 Pages |
Abstract
The RSV F vaccine was safe and immunogenic in pregnant guinea pigs and supported robust transplacental antibody transfer to their pups. Relative concentration of antibodies in the pups was observed even in the presence of high levels of maternal antibody. Guinea pigs may be an important safety and immunogenicity model for preclinical assessment of candidate vaccines for maternal immunization.
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Authors
Gregory M. Glenn, Louis F. Fries, Gale Smith, Eloi Kpamegan, Hanxin Lu, Mimi Guebre-Xabier, Somia P. Hickman, David Flyer,