Article ID Journal Published Year Pages File Type
10963597 Vaccine 2015 7 Pages PDF
Abstract

- VP2 from several serotypes can be expressed on bluetongue virus DISA vaccine.
- Exchange of VP2 from some serotypes on bluetongue virus DISA vaccine is not possible.
- Chimeric VP2 of BTV1 and BTV16 is functional in vitro and in vivo.
- BTV with chimeric VP2 is neutralized by sera against both parental serotypes.
- BTV DISA vaccine with chimeric VP2 induces nAbs against both parental serotypes.
Related Topics
Life Sciences Immunology and Microbiology Immunology
Authors
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