Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10963597 | Vaccine | 2015 | 7 Pages |
Abstract
- VP2 from several serotypes can be expressed on bluetongue virus DISA vaccine.
- Exchange of VP2 from some serotypes on bluetongue virus DISA vaccine is not possible.
- Chimeric VP2 of BTV1 and BTV16 is functional in vitro and in vivo.
- BTV with chimeric VP2 is neutralized by sera against both parental serotypes.
- BTV DISA vaccine with chimeric VP2 induces nAbs against both parental serotypes.
Keywords
Related Topics
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Immunology and Microbiology
Immunology
Authors
Femke Feenstra, Janny S. Pap, Piet A. van Rijn,