The European I-MOVE Multicentre 2013-2014 Case-Control Study. Homogeneous moderate influenza vaccine effectiveness against A(H1N1)pdm09 and heterogenous results by country against A(H3N2)

Article ID	Journal	Published Year	Pages	File Type
10963924	Vaccine	2015	10 Pages	PDF

Abstract

The results suggest a moderate 2013-2014 influenza VE against A(H1N1)pdm09 and a low VE against A(H3N2). The A(H3N2) estimates were heterogeneous among study sites. Larger sample sizes by study site are needed to prevent statistical heterogeneity, decrease variability and allow for two-stage pooled VE for all subgroup analyses.

Keywords

MCCs EMA ARI ILI 95% CI Hemagglutination Inhibition Assay Influenza like illness European Medicines agency European Union Vaccine effectiveness Influenza vaccine effectiveness ISO degrees of freedom World Health Organization International Organization for Standardization Test-negative design Acute respiratory infection 95% confidence intervals Multicentre study odds ratio influenza vaccine polymerase chain reaction PCR WHO

Related Topics

Life Sciences Immunology and Microbiology Immunology

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The European I-MOVE Multicentre 2013-2014 Case-Control Study. Homogeneous moderate influenza vaccine effectiveness against A(H1N1)pdm09 and heterogenous results by country against A(H3N2)

Authors

Marta Valenciano, Esther Kissling, Annicka Reuss, Silvia Jiménez-Jorge, Judit K. Horváth, Joan M.O. Donnell, Daniela Pitigoi, Ausenda Machado, Francisco Pozo, I-MOVE Multicentre Case Control Study Team I-MOVE Multicentre Case Control Study Team,