| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10964402 | Vaccine | 2014 | 8 Pages |
Abstract
The J5dLPS/OMP vaccine elicits high titers of serum anti-endotoxin antibodies in cows that is passed to the colostrum. This BC enriched in anti-core LPS antibodies has the potential to reduce endotoxemia and ameliorate endotoxin-related systemic inflammation in patients with impaired gut barrier function. Since this vaccine is significantly more immunogenic than the J5 Bacterin® vaccine, this J5dLPS/OMP vaccine might prove to be more useful for veterinary indications as well.
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Authors
Alan S. Cross, Hubert J. Karreman, Lei Zhang, Zeil Rosenberg, Steven M. Opal, Andrew Lees,