Article ID Journal Published Year Pages File Type
10964497 Vaccine 2015 9 Pages PDF
Abstract
These findings imply that HIV-1 vaccine strategies designed to target structurally constrained T-cell epitopes may be further challenged by clade-driven outcomes in specific HLA-restricted Gag epitopes. Equally, the data are line with slower HIV-1 disease progression in clade A infection; and raise hope that increased selective pressure on Gag may be protective irrespective of host HLA alleles.
Related Topics
Life Sciences Immunology and Microbiology Immunology
Authors
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