Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10964692 | Vaccine | 2014 | 8 Pages |
Abstract
Routine serotyping and sequence typing in Scotland allowed the assessment of the relationship between the capsule and the clones in the post vaccination era. Changes in the distribution of serotypes post PCV7 introduction appear to be driven by associations between serotypes and STs prior to PCV7 introduction. This has implications for the possible effects of the introduction of higher valency vaccines and could aid in predicting replacement serotypes in IPD.
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Authors
Karen E. Lamb, Stefan Flasche, Mathew Diggle, Donald Inverarity, David Greenhalgh, Johanna M. Jefferies, Andrew Smith, Giles F.S. Edwards, Barbara Denham, Jim McMenamin, Eisin McDonald, Tim J. Mitchell, Stuart C. Clarke, Chris Robertson,