| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10964781 | Vaccine | 2014 | 12 Pages |
Abstract
HPV-16 and -18 antibody responses were lower when additional HPV L1 VLPs were added to the HPV-16/18 AS04-adjuvanted vaccine. Immune interference is a complex phenomenon that cannot always be overcome by changing the antigen dose or adjuvant system.
Keywords
CD40LVLPSAEMPLGMTCTRLPBNATetravalent vaccineQS21TNFgeometric mean antibody titerpseudovirion-based neutralization assayCervical intraepithelial neoplasiaATPSafetyImmunogenicityinterferonIFNinterleukinaccording-to-protocolanalysis of varianceANOVAImmune interferenceELISAEnzyme-linked immunosorbent assayCinVirus-like particleadverse eventNumberSerious adverse eventconfidence intervaltumor necrosis factorCD40 ligandmonthsNo.ELISA unitsBivalent vaccineHuman papillomavirus vaccinepolymerase chain reactionPCRHuman papillomavirusHPVControl
Related Topics
Life Sciences
Immunology and Microbiology
Immunology
Authors
Pierre Van Damme, Geert Leroux-Roels, Philippe Simon, Jean-Michel Foidart, Gilbert Donders, Karel Hoppenbrouwers, Myron Levin, Fabian Tibaldi, Sylviane Poncelet, Philippe Moris, Francis Dessy, Sandra L. Giannini, Dominique Descamps, Gary Dubin,