| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10965106 | Vaccine | 2015 | 8 Pages |
Abstract
The improved immune response to PhtD vaccine containing the AS02V adjuvant system in comparison to alum suggests that the reduced immune response to vaccines in older adults can be partially restored to the response level observed in young adults. ClinicalTrials.gov identifiers: NCT00307528/NCT01767402.
Keywords
Pneumococcal histidine triad protein DPhtDTNFGMCQS21MPLGM-CSFATPAdjuvantStreptococcus pneumoniaeImmunosenescenceinterferonIFNinterleukinaccording-to-protocolEnzyme-linked immunosorbent assayELISAPneumoniaadjuvant Systemadverse eventtumour necrosis factorgranulocyte-macrophage colony-stimulating factorgeometric mean antibody concentrationconfidence intervalVaccinePneumococcal conjugate vaccinehuman immunodeficiency virusHIVPCV
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Authors
Isabel Leroux-Roels, Jeanne-Marie Devaster, Geert Leroux-Roels, Vincent Verlant, Isabelle Henckaerts, Philippe Moris, Philippe Hermand, Pascale Van Belle, Jan T. Poolman, Pierre Vandepapelière, Yves Horsmans,