Use of adenovirus as a model system to illustrate a simple method using standard equipment and inexpensive excipients to remove live virus dependence on the cold-chain

This paper describes the use of Adenovirus (itself fast becoming a vector of choice for a new generation of vaccines) as a model system, and identifies non-toxic, inexpensive excipients which are compatible with current manufacturing processes which could be instrumental in removing the dependence upon the cold chain.