Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10965720 | Vaccine | 2014 | 9 Pages |
Abstract
The study highlights the high prevalence of RV in children with gastroenteritis in Kolkata. The circulating genotypes have changed over the time with predominance of G9 and G2 strains during 2011-2013. The current G2, G9 and G1 Kolkata strains shared low amino acid homologies with current vaccine strains. Although there is substantial evidence for cross protection of vaccines against a variety of strains, still the strain variation should be monitored post vaccine introduction to determine if it has any impact on vaccine effectiveness.
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Authors
Satarupa Mullick, Paulami Mandal, Mukti Kant Nayak, Souvik Ghosh, Papiya De, K. Rajendran, Mihir K. Bhattacharya, Utpala Mitra, Thandavarayan Ramamurthy, Nobumichi Kobayashi, Mamta Chawla-Sarkar,