| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10966383 | Vaccine | 2013 | 7 Pages |
Abstract
Our findings indicate that the NTS-DBL2X region of VAR2CSA can elicit strain-transcending anti-adhesion antibodies and suggest that the combination of the two major variants used here could represent the basis for an effective bivalent VAR2CSA-based vaccine.
Keywords
NTSiPTPVAR2CSAPfEMP1CSPGMFIDSMPBSBSAbovine serum albuminCSAPregnancyInter-domainDuffy binding-likeN-terminal sequenceDBLmedian fluorescence intensityPhosphate buffered salineMalariaPlacental malariaVaccinePlasmodium falciparumPlasmodium falciparum erythrocyte membrane protein 1chondroitin sulfate Achondroitin sulfate proteoglycan
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Authors
Justin Doritchamou, Pascal Bigey, Morten Agertoug Nielsen, Sédami Gnidehou, Sem Ezinmegnon, Aurore Burgain, Achille Massougbodji, Philippe Deloron, Ali Salanti, Nicaise Tuikue Ndam,